Sausville, E.: search on Z-Library

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1

Summary of Breakout Session B: Regulatory Expectations for CGMP

Sausville, R., Cazeault, C.

Journal:

PDA Journal of Pharmaceutical Science and Technology

Year:

2011

Language:

english

File:

PDF, 404 KB

english, 2011

2

Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

Brian K. Adams, Eva M. Ferstl, Matthew C. Davis, Marike Herold, Serdar Kurtkaya, Richard F. Camalier, Melinda G. Hollingshead, Gurmeet Kaur, Edward A. Sausville, Frederick R. Rickles, James P. Snyder,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 508 KB

english, 2004

3

Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin

Sausville, Edward, Tomaszewski, Joseph, Ivy, Percy

Journal:

Current Cancer Drug Targets

Year:

2003

Language:

english

File:

PDF, 91 KB

english, 2003

4

Natural Products and Derivatives as Leads to Cell Cycle Pathway Targets in Cancer Chemotherapy

Newman, David, Cragg, Gordon, Holbeck, Susan, Sausville, Edward

Journal:

Current Cancer Drug Targets

Year:

2002

Language:

english

File:

PDF, 260 KB

english, 2002

5

Jasplakinolide's Inhibition of the Growth of Prostate Carcinoma Cells In Vitro With Disruption of the Actin Cytoskeleton

Senderowicz, A. M. J., Kaur, G., Sainz, E., Laing, C., Inman, W. D., Rodriguez, J., Crews, P., Malspeis, L., Grever, M. R., Sausville, E. A., Duncan, K. L. K.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1995

Language:

english

File:

PDF, 1.78 MB

english, 1995

6

S IGNAL T RANSDUCTION –D IRECTED C ANCER T REATMENTS *

Sausville, Edward A., Elsayed, Yusri, Monga, Manish, Kim, George

Journal:

Annual Review of Pharmacology

Year:

2003

Language:

english

File:

PDF, 471 KB

english, 2003

7

Developmental Therapeutics Program at the NCI: Molecular Target and Drug Discovery Process

M. Monga, E. A. Sausville

Journal:

Year:

2003

File:

PDF, 51 KB

2003

8

Benign prostatic hyperplasia and prostate cancer: an overview for primary care physicians

J. Sausville, M. Naslund

Journal:

International Journal of Clinical Practice

Year:

2010

Language:

english

File:

PDF, 205 KB

english, 2010

9

A cDNA microarray gene expression database for cancer drug discovery

Weinstein, J.N., Scherf, U., Ross, D., Waltham, M., Reinhold, R., Zhou, Y., Scudiero, D.A., Smith, L.H., Lee, J.K., Shalon, D., Lashkari, D., Eisen, M., Myers, T.M., Sausville, E.A., Botstein, D., Bro

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 91 KB

english, 1999

10

Expression of the hypoxia inducible factor-1alpha in head and neck squamous cell carcinoma

Ruben Cabanillas, Marta Canel, Juan Pablo Rodrigo, Maria Dolores Chiara, Carlos Suarez-Nieto, Edward A. Sausville, Carter Van Waes

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2004

Language:

english

File:

PDF, 36 KB

english, 2004

11

Mining the National Cancer Institute's Tumor-Screening Database: Identification of Compounds with Similar Cellular Activities

Rabow, Alfred A., Shoemaker, Robert H., Sausville, Edward A., Covell, David G.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 1.16 MB

english, 2002

12

Paullones, a Series of Cyclin-Dependent Kinase Inhibitors: Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity

Schultz, Christiane, Link, Andreas, Leost, Maryse, Zaharevitz, Daniel W., Gussio, Rick, Sausville, Edward A., Meijer, Laurent, Kunick, Conrad

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

13

INITIAL EXPERIENCE IN RENAL CRYOSURGERY FOR LARGE RENAL LESIONS.

Sausville, Justin, Borin, James, Phelan, Michael W

Journal:

The Journal of Urology

Year:

2008

Language:

english

File:

PDF, 123 KB

english, 2008

14

Use of “Virtual” High-Dose-Rate (HDR) Brachytherapy via Spatially Fractionated GRID Radiation Therapy (SFGRT) as Part of Neoadjuvant Therapy in Poor Prognosis, Bulky Sarcomas

Snider, J.W., Francis, M., Hanna, N., Alexander, H., Sausville, E., Amin, P.P., Regine, W.F.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2014

Language:

english

File:

PDF, 54 KB

english, 2014

15

Phase I Study of Folate Conjugate EC145 (Vintafolide) in Patients With Refractory Solid Tumors

LoRusso, P. M., Edelman, M. J., Bever, S. L., Forman, K. M., Pilat, M., Quinn, M. F., Li, J., Heath, E. I., Malburg, L. M., Klein, P. J., Leamon, C. P., Messmann, R. A., Sausville, E. A.

Journal:

Journal of Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 106 KB

english, 2012

16

Disparities in black and white patients with multiple myeloma referred for autologous hematopoietic transplantation: A single center study

Bhatnagar, Vishal, Wu, Yin, Goloubeva, Olga G., Ruehle, Kathleen T., Milliron, Todd E., Harris, Carolynn G., Rapoport, Aaron P., Yanovich, Saul, Sausville, Edward A., Baer, Maria R., Badros, Ashraf Z.

Journal:

Year:

2015

Language:

english

File:

PDF, 255 KB

english, 2015

17

State of the Art: Oncogenes, Growth Factors, and Lung Cancer

Sausville, Edward, Fisher, James

Journal:

Year:

1987

Language:

english

File:

PDF, 414 KB

english, 1987

18

A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone

Pidugu, Lakshmi Swarna Mukhi, Mbimba, J.C. Emmanuel, Ahmad, Muqeet, Pozharski, Edwin, Sausville, Edward A., Emadi, Ashkan, Toth, Eric A.

Journal:

BMC Structural Biology

Year:

2016

Language:

english

File:

PDF, 3.11 MB

english, 2016

19

Evaluation of circulating malignant cells provides prognostic information in cutaneous T cell lymphoma

Schechter, GP, Sausville, EA, Fischmann, AB, Soehnlen, F, Eddy, J, Matthews, M, Gazdar, A, Guccion, J, Munson, D, Makuch, R

Journal:

Year:

1987

File:

PDF, 1.71 MB

1987

20

In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC

Ioannis A. Avramis, Garyfallia Christodoulopoulos, Atsushi Suzuki, Walter E. Laug, Ignacio Gonzalez-Gomez, George McNamara, Edward A. Sausville, Vassilios I. Avramis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 1.76 MB

english, 2002

21

Inhibition of CDKs as a Therapeutic Modality

EDWARD A. SAUSVILLE, JILL JOHNSON, MICHAEL ALLEY, DANIEL ZAHAREVITZ, ADRIAN M. SENDEROWICZ

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 3.72 MB

english, 2000

22

DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells

Trapani, V, Patel, V, Leong, C-O, Ciolino, H P, Yeh, G C, Hose, C, Trepel, J B, Stevens, M F G, Sausville, E A, Loaiza-Pérez, A I

Journal:

British Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 221 KB

english, 2003

23

UCN-01 Enhances the In Vitro Toxicity of Clinical Agents in Human Tumor Cell Lines

Anne Monks, Erik D. Harris, Anne Vaigro-Wolff, Curtis D. Hose, John W. Connelly, Edward A. Sausville

Journal:

Investigational New Drugs

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

24

Selective Accumulation of the Endoplasmic Reticulum–Golgi Intermediate Compartment Induced by the Antitumor Drug KRN5500

Masaru Kamishohara, Susan Kenney, Renee Domergue, David T. Vistica, Edward A. Sausville

Journal:

Experimental Cell Research

Year:

2000

Language:

english

File:

PDF, 598 KB

english, 2000

25

Changes in the exposure of tryptophyl and tyrosyl residues in thrombin due to diisopropylphosphorofluoridate and benzamidine inhibitions

German B. Villanueva, C. William Batt, Edward Sausville, Victor Tortorelli, Kenneth Cubelli, William Brunner

Journal:

Biochemical and Biophysical Research Communications

Year:

1975

Language:

english

File:

PDF, 404 KB

english, 1975

26

Phase 1 dose-escalation, pharmacokinetic, and cerebrospinal fluid distribution study of TAK-285, an investigational inhibitor of EGFR and HER2

Patricia LoRusso, Karthik Venkatakrishnan, E. Gabriela Chiorean, Dennis Noe, Jing-Tao Wu, Serap Sankoh, Maria Corvez, Edward A. Sausville

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 471 KB

english, 2014

27

Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors

Sausville, Edward, LoRusso, Patricia, Carducci, Michael, Carter, Judith, Quinn, Mary F., Malburg, Lisa, Azad, Nilofer, Cosgrove, David, Knight, Richard, Barker, Peter, Zabludoff, Sonya, Agbo, Felix, O

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

28

Asparaginase in the treatment of non-ALL hematologic malignancies

Emadi, Ashkan, Zokaee, Hania, Sausville, Edward A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 403 KB

english, 2014

29

Early Development of Cyclin Dependent Kinase Modulators

K.K. Roy, Bentham Science Publisher, E.A. Sausville, Bentham Science Publisher

Journal:

Current Pharmaceutical Design

Year:

2001

Language:

english

File:

PDF, 167 KB

english, 2001

30

The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

Grenert, J. P., Sullivan, W. P., Fadden, P., Haystead, T. A. J., Clark, J., Mimnaugh, E., Krutzsch, H., Ochel, H.-J., Schulte, T. W., Sausville, E., Neckers, L. M., Toft, D. O.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 882 KB

english, 1997

31

Incandescent Lamp Color with High-Intensity Discharge Lamps

Rokosz, F., Sausville, J. W., Van Broekhoven, J.

Journal:

Journal of the Illuminating Engineering Society

Year:

1973

Language:

english

File:

PDF, 396 KB

english, 1973

32

State of the Art: Clinical Review of Lung Cancer

Sausville, Edward, Scoggin, Charles

Journal:

Year:

1987

Language:

english

File:

PDF, 396 KB

english, 1987

33

Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin

Bubb, Michael R., Senderowicz, Adrian M J, Sausville, Edward a., Duncan, Kimberly L K, Korn, Edward D.

Journal:

Journal of Biological Chemistry

Year:

1994

Language:

english

File:

PDF, 384 KB

english, 1994

34

P-D6 Lasting Reduction Of HIV Replication In Chronically Infected Humanized Mice (HSC-NSG) By Targeting Transcription With A CDK9 Inhibitor

Medina-Moreno, Sandra, Le, Nhut, Zapata, Juan, Bryant, Joseph, Sausville, Edward, Redfield, Robert, Heredia, Alonso

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2017

Language:

english

File:

PDF, 2.69 MB

english, 2017

35

Benzodithiophenes Induce Differentiation and Apoptosis in Human Leukemia Cells

Jing, Yongkui, Hellinger, Nella, Xia, Lijuan, Monks, Anne, Sausville, Edward A., Zelent, Arthur, Waxman, Samuel

Journal:

Cancer Research

Year:

2005

Language:

english

File:

PDF, 611 KB

english, 2005

36

Optimizing pegylated asparaginase use: An institutional guideline for dosing, monitoring, and management

Bade, Najeebah A, Lu, Crystal, Patzke, Ciera L, Baer, Maria R, Duong, Vu H, Law, Jennie Y, Lee, Seung T, Sausville, Edward A, Zimrin, Ann B, Duffy, Alison P, Lawson, Justin, Emadi, Ashkan

Journal:

Journal of Oncology Pharmacy Practice

Year:

2019

File:

PDF, 541 KB

2019

37

Determination of MS-275, a novel histone deacetylase inhibitor, in human plasma by liquid chromatography–electrospray mass spectrometry

Kyunghwa Hwang, Milin R Acharya, Edward A Sausville, Suoping Zhai, Eunhee W Woo, Jürgen Venitz, William D Figg, Alex Sparreboom

Journal:

Journal of Chromatography B

Year:

2004

Language:

english

File:

PDF, 100 KB

english, 2004

38

Jasplakinolide: interaction with radiation and hyperthermia in human prostate carcinoma and Lewis lung carcinoma

Hideya Takeuchi, Gulshan Ara, Edward A. Sausville, Beverly Teicher

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 289 KB

english, 1998

39

Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process

Yu, Chunrong, Rahmani, Mohamed, Almenara, Jorge, Sausville, Edward A, Dent, Paul, Grant, Steven

Journal:

Year:

2003

Language:

english

File:

PDF, 511 KB

english, 2003

40

A phase I/II study of carfilzomib 2–10-min infusion in patients with advanced solid tumors

Papadopoulos, Kyriakos P., Burris, Howard A., Gordon, Michael, Lee, Peter, Sausville, Edward A., Rosen, Peter J., Patnaik, Amita, Cutler, Richard E., Wang, Zhengping, Lee, Susan, Jones, Suzanne F., In

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 491 KB

english, 2013

41

Simultaneous Bilateral Native Nephrectomy and Living Donor Renal Transplantation are Successful for Polycystic Kidney Disease: The University of Maryland Experience

Kramer, Andrew, Sausville, Justin, Haririan, Abdolreza, Bartlett, Stephen, Cooper, Matthew, Phelan, Michael

Journal:

The Journal of Urology

Year:

2009

Language:

english

File:

PDF, 84 KB

english, 2009

42

Human Small-Cell Lung Cancers Show Amplification and Expression of the N-myc Gene

Marion M. Nau, Burke J. Brooks, Desmond N. Carney, Adi F. Gazdar, James F. Battey, Edward A. Sausville and John D. Minna

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.11 MB

english, 1986

43

Human small-cell lung cancers show amplification and expression of the N-myc gene.

Nau, M. M., Brooks, B. J., Carney, D. N., Gazdar, A. F., Battey, J. F., Sausville, E. A., Minna, J. D.

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.33 MB

english, 1986

44

Looking for answers: the current status of neoadjuvant treatment in localized soft tissue sarcomas

Nathenson, Michael J., Sausville, Edward

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 643 KB

english, 2016

45

Phase II trial of suramin, leuprolide, and flutamide in previously untreated metastatic prostate cancer.

Dawson, N A, Figg, W D, Cooper, M R, Sartor, O, Bergan, R C, Senderowicz, A M, Steinberg, S M, Tompkins, A, Weinberger, B, Sausville, E A, Reed, E, Myers, C E

Journal:

Journal of Clinical Oncology

Year:

1997

Language:

english

File:

PDF, 711 KB

english, 1997

46

Evolving approaches to cancer drug discovery and development at the National Cancer Institute, USA

Sausville, E. A., Feigal, E.

Journal:

Annals of Oncology

Year:

1999

File:

PDF, 531 KB

1999

47

Relapsed Philadelphia Chromosome-Positive Pre-B-ALL after CD19-Directed CAR-T Cell Therapy Successfully Treated with Combination of Blinatumomab and Ponatinib

El Chaer, Firas, Holtzman, Noa G., Sausville, Edward A., Law, Jennie Y., Lee, Seung Tae, Duong, Vu H., Baer, Maria R. , Koka, Rima, Singh, Zeba N., Hardy, Nancy M., Emadi, Ashkan

Journal:

Acta Haematologica

Year:

2019

File:

PDF, 120 KB

2019

48

Phase II trial of intermittent high-dose recombinant interferon alfa-2a in mycosis fungoides and the Sézary syndrome.

Kohn, E C, Steis, R G, Sausville, E A, Veach, S R, Stocker, J L, Phelps, R, Franco, S, Longo, D L, Bunn, P A, Ihde, D C

Journal:

Journal of Clinical Oncology

Year:

1990

Language:

english

File:

PDF, 460 KB

english, 1990

49

ChemInform Abstract: 2-Substituted Paullones: CDK1/Cyclin B-Inhibiting Property and in vitro Antiproliferative Activity.

Conrad Kunick, Christiane Schultz, Thomas Lemcke, Daniel W. Zaharevitz, Rick Gussio, Ravi K. Jalluri, Edward A. Sausville, Maryse Leost, Laurent Meijer

Journal:

Year:

2000

File:

PDF, 28 KB

2000

50

Experimental design and interaction analysis of combination studies of drugs with log-linear dose responses

Hong-Bin Fang, Douglas D. Ross, Edward Sausville, Ming Tan

Journal:

Statistics in Medicine

Year:

2008

Language:

english

File:

PDF, 183 KB

english, 2008

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